MONK
30th May 2005, 11:54
Post on UD (http://forum.grid.org/phpBB/viewtopic.php?t=15876&start=40)
Post on WCG (not world cyber games) (http://www.worldcommunitygrid.org/forums/wcg/viewthread?thread=2882)
OK so we are somewhere between 55% and 67% of the way through the human proteome folding project. The above links show the post of which an extract is below. The project should rap up in the next 3-6 months depending on how much the project drops off over the hot summer as people save power cool rooms and don't spend as much time inside. My personal guess is about 4 months finishing mid september to october.
The posts contain a list of some of the thigs that the project is looking into. For instance Bifidobacterium longum which I am told is important for having a healthy intestine!
Non-human proteomes on the grid, and their importance to human health
So far we’ve talked a lot about the human health side of this project, i.e. we’ve talked about the human proteome and what predicting human protein structures can hope to accomplish.
This project is devoted primarily to the human proteome and understanding the human proteome by predicting the structure of proteins of unknown function in the human proteome.
We are also, however, folding the proteins of unknown function in over 60 other complete genomes that we feel have an important impact on human quality of life. I list below a sampling of the other genomes we’re exploring as part of the proteome folding project on the worldcommunitygrid. I’ll give a sentence or two about each of them, but each organism has a lot of reasons for further study. I could give you the full list, but these represent a good mix. In general there are 4 categories of proteins we’re folding (all important for improving people’s health and/or quality of life):
1. Human proteins: Priority 1 for this project. Contribute to the understand the human proteome with structure prediction.
2. Human pathogens: understanding these nasty guys contributes to our efforts to knocking them out.
3. Environmental: More and more we are realizing that the living things in any ecosystem have methods for responding to pollution and other human influences in ways that lead us to believe that bioremediation of toxic waste sites is on the horizon. Understanding bugs/bacteria and archaea involved in the environment is the first step.
4. Model systems: These are organisms that are studied in the lab because they are safe, easy to work with and easy to manipulate. Much of what we understand about genetics and biology at large comes from studying these organisms.
Now for a few examples of non human proteomes on the grid:
(if you don’t see a genome/proteome listed here it doesn’t mean we’re not folding it, just that I’m sick of typing ... over 60 complete genomes were processed as part of this project)
Post on WCG (not world cyber games) (http://www.worldcommunitygrid.org/forums/wcg/viewthread?thread=2882)
OK so we are somewhere between 55% and 67% of the way through the human proteome folding project. The above links show the post of which an extract is below. The project should rap up in the next 3-6 months depending on how much the project drops off over the hot summer as people save power cool rooms and don't spend as much time inside. My personal guess is about 4 months finishing mid september to october.
The posts contain a list of some of the thigs that the project is looking into. For instance Bifidobacterium longum which I am told is important for having a healthy intestine!
Non-human proteomes on the grid, and their importance to human health
So far we’ve talked a lot about the human health side of this project, i.e. we’ve talked about the human proteome and what predicting human protein structures can hope to accomplish.
This project is devoted primarily to the human proteome and understanding the human proteome by predicting the structure of proteins of unknown function in the human proteome.
We are also, however, folding the proteins of unknown function in over 60 other complete genomes that we feel have an important impact on human quality of life. I list below a sampling of the other genomes we’re exploring as part of the proteome folding project on the worldcommunitygrid. I’ll give a sentence or two about each of them, but each organism has a lot of reasons for further study. I could give you the full list, but these represent a good mix. In general there are 4 categories of proteins we’re folding (all important for improving people’s health and/or quality of life):
1. Human proteins: Priority 1 for this project. Contribute to the understand the human proteome with structure prediction.
2. Human pathogens: understanding these nasty guys contributes to our efforts to knocking them out.
3. Environmental: More and more we are realizing that the living things in any ecosystem have methods for responding to pollution and other human influences in ways that lead us to believe that bioremediation of toxic waste sites is on the horizon. Understanding bugs/bacteria and archaea involved in the environment is the first step.
4. Model systems: These are organisms that are studied in the lab because they are safe, easy to work with and easy to manipulate. Much of what we understand about genetics and biology at large comes from studying these organisms.
Now for a few examples of non human proteomes on the grid:
(if you don’t see a genome/proteome listed here it doesn’t mean we’re not folding it, just that I’m sick of typing ... over 60 complete genomes were processed as part of this project)